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    Johnson and Johnson stops making Evolence

    Tag Archives: Injectable fillers

    This story is taken from the Wall Street Journal

    A Johnson & Johnson (JNJ) unit has decided to stop making and selling a product called Evolence, used to fill facial lines in cosmetic procedures.

    Ortho Dermatologics, a division of J&J’s Ortho-McNeil-Janssen Pharmaceuticals, has a note on its Web site regarding the withdrawal, which it said was announced on Tuesday. The company confirmed the move in a statement.

    The Evolence halt is part of an effort “to refine strategic priorities and focus investment on other growth opportunities,” Ortho Dermatologics said.

    Many options for future management were explored before this decision was made, the company said. It added that patients and medical professionals can be assured that Evolence “remains effective for the correction of moderate to deep wrinkles and folds with a favorable safety profile.”

    The facial filler gained approval from the U.S. Food and Drug Administration in June 2008, but it has been available in certain international markets since 2004. The U.S. arrival coincided with a rough time in the market for cosmetic medical products, which usually are not covered by insurers and came under pressure due to the recession.

    J&J announced on Tuesday that it plans to lay off as many as 8,200 workers worldwide as part of a plan to save up to $1.7 billion in 2011.

    -By Jon Kamp, Dow Jones Newswires

    Treatments with injectable fillers, such as Juvederm, Restylane, Radiesse, and Evolence, not to mention others, can restore a youthful appearance to the lips, nasolabial folds, marionette lines, midface, jowls and lower eyelids, with minimal to no downtime.  Many patients avoid these treatments, though, because they have heard horror stories from friends or colleagues about the pain associated with these treatments.  Suffice it to say, this needn’t be the case – there are steps your plastic surgeon can take to make these treatments more comfortable.

    Recently, BioForm Medical, Inc., makers of Radiesse, received approval from the Food and Drug Administration to mix the filler with lidocaine, an injectable local anesthetic, prior to injection into the skin.  This approval was based on a large study of patients, in which 100% of patients reported feeling less pain when Radiesse was pre-mixed with lidocaine.  Many plastic surgeons, including me, have begun to pre-mix lidocaine with all fillers, including Juvederm, Restylane, and Evolence, not to mention Radiesse, prior to injecting into patients.  The results of treatment are still great, but patients are significantly more comfortable during treatment.

    Others things your plastic surgeon can do to make your treatment with injectable fillers more comfortable include:
    •    Using topical anesthetic gel for at least 30 minutes prior to commencing any injections.
    •    Augmenting treatment with topical anesthetic gel with injections of local anesthetic into nerves above and below the lips.
    •    Using small gauge needles and slow injection techniques

    Combining all of these treatments can ensure that you’ll not only look fantastic after your treatment with injectable fillers, but you’ll feel pretty good during the treatment too!

    Discover Dallas Best Plastic Surgeon | Sam Jejurikar MD


    <!–[endif]–>Evolence®, a collagen-based injectable filler used for the correction of facial wrinkles and folds, has recently been given permission by the FDA to advertise results lasting 12 months. While relatively new to the United States, Evolence® has been available in Canada and Europe for many years.

    The filler uses porcine (pig) collagen to restore a more youthful appearance. This new generation collagen filler is injected into the mid-to-deep layers of the skin for the correction of moderate to deep facial wrinkles and folds, such as nasolabial folds. Results are visible immediately after treatment.

    The most common side effects include mild swelling, redness, and pain. A skin test is not required because porcine collagen is the most genetically similar to human collagen.

    Evolence® is now clinically proven to last for 12 months! Call 214-827-2814 to learn about our special rates!

    Dysport is the first competitor to Botox  in the U.S., but has been used in Europe in for several years.  These products seem relatively similar; a great analogy is Coke versus Pepsi. Competition can only be a good thing for pricing, though, and  that should become evident over the next couple of years, as more products are released.

    That being said, the major differences between Dysport and Botox seem to be the following:

    1) A faster onset of effects is noted with Dysport in some patients.  Whereas Botox may take 3-7 days to take effect, some patients who receive Dysport see results in a day.

    2) Some studies indicate a slightly longer duration of effect, but not all of them.  Clinical experience in the U.S. over the next several months will help guide consensus on this.

    3) The dosing for Botox and Dysport is different.  A Botox unit is not equivalent to a Dysport unit.  The converision is approximately 2.5 Dysport units to 1 Botox unit, but there is some variation between the upper and lower face, as well as variations based on the patient’s facial muscle mass.

    A recently published study showed Dysport is highly effective in women, as well as highly effective and longer lasting in African Americans.  It also demonstrated that Dysport was highly effective in patients who previously had a good response to Botox.Right now is a great time to try Dysport – our office is offering $50 off your initial treatment.  If you’ve had a good response to Botox in the past, or have simply wanted to try it, the time may be right to try Dysport.

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